Glucagen Novo Hypokit 1mg/1ml .Novo Nordisk– glucagon hydrochloride
GlucaGen HypoKit contains glucagon (rys) hydrochloride. The abbreviation “rys” indicates the method of genetic engineering used to manufacture the glucagon.
Glucagon is a natural hormone, which has the opposite effect to insulin in the human body. It helps the body to convert glycogen into glucose (sugar) in the liver. Glucose is then released into the blood stream. This means that GlucaGen HypoKit will only work to increase blood sugar if there are stores of glycogen in the liver.
Glucagon also reduces the movements of the smooth muscle in the digestive system and stimulates the production of insulin by the beta cells of the pancreas.
GlucaGen HypoKit is used to treat severe hypoglycaemia (extremely low blood sugar levels, or “hypos”) in people using insulin or taking tablets to control their diabetes, who have become unconscious.
GlucaGen HypoKit is also used during medical investigations of the gastrointestinal tract to relax and slow down the movements of the stomach and bowel. This makes it easier for your doctor to investigate your digestive tract.
GlucaGen HypoKit is also used to stimulate the production of insulin by the beta cells. It can therefore be used to find out how well the beta cells in the pancreas are working.
Your doctor may have prescribed GlucaGen HypoKit for another reason.
GlucaGen contains an injection of glucagon, and works by triggering the liver to release stored sugar, raising blood sugar levels. It is injected under the skin, similar to how insulin is injected. Do not use GlucaGen if you are allergic to either glucagon or lactose, have a tumor of the adrenal gland called a pheochromocytoma, or have a tumor of the pancreas called insulinoma.
Uses and dosage :
Dissolve the compacted powder in the accompanying solvent, as described in section 6.6.
Therapeutic indication (Severe hypoglycaemia):
Administer by subcutaneous or intramuscular injection. The patient will normally respond within 10 minutes. When the patient has responded to the treatment, give oral carbohydrate to restore the liver glycogen and prevent relapse of hypoglycaemia. If the patient does not respond within ten minutes, intravenous glucose should be given.
- The usual dose for adults and children who weigh more than 55 pounds (25 kg) is 1 mg (1 mL). Use the content of the full syringe (1 mL).
- The usual dose for children who weigh less than 55 pounds (25 kg) is 0.5 mg (0.5 mL). Gently push the plunger until it is at the 0.5 mL mark on the syringe to ensure there is 0.5 mL liquid left in the syringe.
After end of the diagnostic procedure oral carbohydrate should be given, if this is compatible with the diagnostic procedure applied.
If you do not know how much the child weighs:
- Give a child under 6 years of age 0.5 mg (0.5 mL).
- Give a child 6 years of age and older 1 mg (1 mL).
GlucaGen may cause serious side effects, including:
- High blood pressure. High blood pressure is common after taking GlucaGen® and can be severe
- Low blood sugar. GlucaGen® can cause low blood sugar in patients with tumors in their pancreas called insulinomas and glucagonomas by making too much insulin in their bodies
- Allergic reactions. Symptoms of a serious allergic reaction to GlucaGen® may include rash, difficulty breathing, or low blood pressure (hypotension)
The most common side effects of GlucaGen® include:
- and temporary fast heartbeat or pounding in your chest (tachycardia)